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遗传发育与细胞生物学系

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梁成光

出生年月：
学位学历：博士研究生
职       称：教授
导       师：博士生导师 硕士生导师

研究方向（领域）：

发育生物学与细胞生物学

学术（社会）兼职：

目前是国际生殖研究协会PI级会员、中国生理学会生殖学科专业委员会理事、中国动物学会生殖生物学分会理事、中国动物学会细胞与分子显微技术学分会理事、内蒙古生物工程学会副理事长。同时担任Biology of Reproduction，Human Reproduction，Molecular Reproduction & Development，Cell Death & Disease，Environmental Toxicology等多种专业期刊的编辑和审稿人职务。

联系方式：

liangcg@imu.edu.cn，+86-471-3679862

主持项目：

  1. 国家973计划前期研究专项

  2. 国家自然科学基金面上项目/地区项目

  3. 教育部新世纪优秀人才支持计划

  4. 内蒙古自治区草原英才工程

  5. 内蒙古自治区重大基础研究开放课题和自然基金重大项目

  6. 内蒙古自治区杰出青年培育基金

  7. 内蒙古自治区关键技术攻关计划项目

  8. 教育部科学技术研究重点项目


代表性论著：

全部论文可通过如下链接查询http://www.ncbi.nlm.nih.gov/pubmed/?term=cheng-guang+liang

  1. Lei Ge, Yu-Qing Gao, Zhe Han, Shu-Jun Liu, Xing-Yue Wang, Xiao-Jie Zhang, Rui-Hao Tang, Rui-Feng Zhang, Dui Sun, Bo Feng, De-Jian Zhang*, Cheng-Guang Liang* Administration of olaquindox impairs spermatogenesis and sperm quality by increasing oxidative stress and early apoptosis in mice. Ecotoxicology and Environmental Safety. 2022 Mar Volume 234, 113396

  2. Cheng-Jie Zhou, Dong-Hui Wang, Xiang-Wei Kong, Zhe Han, Xin Hao, Xing-Yue Wang, Xin Wen, Cheng-Guang Liang*. Protein Regulator of Cytokinesis 1 Regulates Chromosome Dynamics and Cytoplasmic Division During Mouse Oocyte Meiotic Maturation and Early Embryonic Development. FEBS Journal. 2020 Dec 07. doi: 10.1111/febs.15458.

  3. Lei Ge, Zhe Han, Yu-Qing Gao, Cheng-Jie Zhou, Dong-Hui Wang, Yu-Zhen Ma, Cheng-Guang Liang*. Sodium nitrite negatively affects reproductive ability and offspring survival in female mice. Toxicology. 2019 Aug 30;427:152284

  4. Cheng-Jie Zhou, Xing-Yue Wang, Zhe Han, Dong-Hui Wang, Yu-Zhen Ma，Cheng-Guang Liang*. Loss of CENPF leads to developmental failure in mouse embryos. Cell Cycle. 2019 Oct;18(20):2784-2799

  5. Xiang-Wei Kong, Dong-Hui Wang, Cheng-Jie Zhou, Hong-Xia Zhou, Cheng-Guang Liang*. Loss of function of KIF1B impairs oocyte meiotic maturation and early embryonic development in mice. Molecular Reproduction & Development 2016 : 83(11):1027-1040

  6. Dong-Hui Wang#, Hong-Xia Zhou# (co-1st author), Shu-Jun Liu, Cheng-Jie Zhou, Xiang-Wei Kong, Zhe Han, Cheng-Guang Liang*. Glial cell line-derived neurotrophic factor supplementation promotes bovine in vitro oocyte maturation and early embryo development. Theriogenology. 2018: 113: 92–101

  7. Zhao J, Wang L, Zhou HX, Liu L, Lu A, Li GP, Schatten H, Liang CG*. Clathrin heavy chain 1 is required for spindle assembly and chromosome congression in mouse oocytes. Microscopy & Microanalysis 2013:19:1364

  8. Han ZM#, Liang CG#, Cheng Y# (contribute equally), Duan X, Zhong Z, Potireddy S, Moncada C, Merali S, Latham KE*. Oocyte spindle proteomics analysis leading to rescue of chromosome congression defects in cloned embryos. J. Proteome Res. 2010:9:6025

  9. Liang CG, Han Z, Cheng Y, Zhong Z, Latham KE*. Effect of ooplasm transfer on paternal genome function in mice. Human Reproduction. 2009:24:2718

  10. Liang CG, Su YQ, Fan HY, Schatten H and Sun QY*. Mechanisms regulating oocyte meiosis resumption: the role of mitogen-activated protein kinase. (Invited Review) Mol Endocrinol. 2007:21:2037

  11. Liang CG, Huo LJ, Zhong ZS, Chen DY, Schatten H, Sun QY*. Cyclic adenosine 3',5'-monophosphate-dependent activation of mitogen-activated protein kinase in cumulus cells is essential for germinal vesicle breakdown of porcine cumulus-enclosed oocytes. Endocrinology. 2005:146:1444

  12. 梁成光 孙青原* （译著）小鼠胚胎操作实验手册 第14章 辅助生殖——卵巢移植、体外受精、人工授精和胞质内精子注射。化学工业出版社 2005：411-434  ISBN:7-5025-7667-3

  13. 梁成光* 《话说克隆技术》 中国劳动社会保障出版社 2013，ISBN：978-7-5167-0808-8



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